Dr Amy Chan
Dr Amy Chan
Postdoctoral Researcher
Inflammasome Lab
After obtaining First Class Honours in 2014 in the Toth lab, Amy completed a year of voluntary research to explore her interests in the field of immunology. Working in collaboration with the Institute for Glycomics at Griffith University, she developed a novel prophylactic vaccine against streptococcus pyogenes. Amy joined the Inflammasome Lab in 2016 for her PhD studies. Her PhD project is unravelling the mysteries of the poorly understood “non-canonical” inflammasome.
CONTACTS AND LINKS
Email: amy.chan@imb.uq.edu.au
Office Telephone: +61 7 3346 2071
AWARDS AND PUBLICATIONS
AWARDS, GRANTS AND PRIZES
2017-2020 Young Science Ambassador Award (Wonder of Science)
2019 Life Science Young Achiever Award (Women in Technology)
2018 & 2019 Tutor Excellence Award (UQ)
2018 People's Choice Award for QLD Women In STEM
2016 Australian Postgraduate Award
2014 Dean’s Commendation for Academic Excellence, The University of Queensland
EDUCATION
2014 BSc Honours (Biochemistry), Supervisor: Professor Istvan Toth, The University of Queensland
2013 Bachelor of Science, The University of Queensland
Ross C, Chan AH, von Pein JB, Maddugoda MP, Boucher D, Schroder K (2022).
Inflammatory Caspases: Toward a Unified Model for Caspase Activation by Inflammasomes. Annual Review of Immunology Apr 26;40:249-269. Pubmed
Bonfim-Melo A, Noordstra I, Gupta S, Chan AH, Jones MJK, Schroder K, Yap AS (2022).
Rapid lamellipodial responses by neighbor cells drive epithelial sealing in response to pyroptotic cell death. Cell Reports Feb 1;38(5):110316. Pubmed
Chan AH, Schroder K (2020).
Inflammasome signaling and regulation of interleukin-1 family cytokines. Journal of Experimental Medicine Jan 6;217(1):e20190314. Pubmed
Ross C, Chan AH, Von Pein J, Boucher D, Schroder K (2018).
Dimerization and auto-processing induce caspase-11 protease activation within the non-canonical inflammasome. Life Science Alliance Dec 6;1(6):e201800237. Pubmed
Boucher D, Chan A, Ross C, Schroder K. (2018).
Quantifying Caspase-1 Activity in Murine Macrophages. Methods in Molecular Biology 1725:163-176. Pubmed
Chan A, Hussein WM, Ghaffar KA, Marasini N, Mostafa A, Eskandari S, Batzloff MR, Good MF, Skwarczynski M, & Toth I (2016).
Structure-activity relationship of lipid core peptide-based Group A Streptococcus vaccine candidates. Bioorganic & Medicinal Chemistry 24(14):3095-3101. Pubmed
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